BDBM171395 US9085576, 29
SMILES Cc1cc(OCC#CC(C)(C)O)cnc1C(=O)Nc1ccc(F)c(c1)C1(C)N=C(N)O[C@H]2C[C@@H]12
InChI Key InChIKey=UXSPFCVHCYSGDI-RZCQNPAPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 171395
Affinity DataIC50: 4.62E+5nMpH: 3.5Assay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 207nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair