BDBM171395 US9085576, 29

SMILES Cc1cc(OCC#CC(C)(C)O)cnc1C(=O)Nc1ccc(F)c(c1)C1(C)N=C(N)O[C@H]2C[C@@H]12

InChI Key InChIKey=UXSPFCVHCYSGDI-RZCQNPAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 171395   

TargetCathepsin D(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM171395(US9085576, 29)
Affinity DataIC50:  4.62E+5nMpH: 3.5Assay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM171395(US9085576, 29)
Affinity DataIC50:  207nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In DepthDetails US Patent