BDBM172 (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis[(3-acetylphenyl)methyl]-5,6-dihydroxy-1,3-diazepan-2-one::(4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis[(3-acetylphenyl)methyl]-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-one::CHEMBL289473::Cyclic Urea
SMILES CC(=O)c1cccc(CN2[C@H](Cc3ccccc3)[C@H](O)[C@@H](O)[C@@H](Cc3ccccc3)N(Cc3cccc(c3)C(C)=O)C2=O)c1
InChI Key InChIKey=GNWGNQFZTKCMNP-NWJWHWDBSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 172
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0600nM ΔG°: -14.5kcal/molepH: 5.5 T: 2°CAssay Description:Ki values were determined with recombinant single-chain dimeric HIV protease and a fluorescent substrate. The use of single-chain dimeric protease a...More data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition of HIV protease, measured by assaying the cleavage of a fluorescent peptide substrate using HPLCMore data for this Ligand-Target Pair