BDBM172328 US9090596, 8

SMILES COC(=O)[C@H]1CCCN1C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O

InChI Key InChIKey=SIUQYAWDXLUCLD-OSPHWJPCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 172328   

TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172328(US9090596, 8)
Affinity DataIC50:  604nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172328(US9090596, 8)
Affinity DataIC50:  240nMAssay Description:The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172328(US9090596, 8)
Affinity DataIC50:  5.80nMAssay Description:The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172328(US9090596, 8)
Affinity DataIC50:  37nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In DepthDetails US Patent