BDBM172369 US9090596, 50

SMILES CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O

InChI Key InChIKey=MMVFNAGMKWQAKS-NRFANRHFSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 172369   

TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172369(US9090596, 50)
Affinity DataIC50:  312nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172369(US9090596, 50)
Affinity DataIC50:  700nMAssay Description:The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172369(US9090596, 50)
Affinity DataIC50:  1.40nMAssay Description:The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172369(US9090596, 50)
Affinity DataIC50:  72nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In DepthDetails US Patent