BDBM172726 US9096515, 33a -(R)-Isomer::US9296681, 33a-(R)-Isomer

SMILES C[C@@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=OZLLUGNMXJLQIE-AWEZNQCLSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 172726   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172726(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Affinity DataKi:  0.910nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172726(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Affinity DataKi:  0.910nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172726(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Affinity DataKi:  2.30nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172726(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Affinity DataKi:  2.30nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172726(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Affinity DataKi:  30.3nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172726(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Affinity DataKi:  30.3nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In DepthDetails US Patent