BDBM173548 1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)phenyl)-3-(3,4-dichlorophenyl) thiourea (5)

SMILES COc1cccc(NC(=S)Nc2ccc(cc2)C(c2c(O)c3ccccc3oc2=O)c2c(O)c3ccccc3oc2=O)c1

InChI Key InChIKey=RZLQOOCNTHRDRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173548   

LigandPNGBDBM173548(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibition of Baker's yeast alpha-glucosidase using pNPG as substrate assessed as release of p-nitrophenol preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara

LigandPNGBDBM173548(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50:  2.53E+4nMpH: 6.8 T: 2°CAssay Description:The enzyme inhibition was evaluated according to the method previously reported by Taha et al. with slight modification. Various concentration of tes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed