BDBM17369 1,2,4-Triazole Compound, 27::5-{[(3,4-difluorophenyl)methyl]sulfanyl}-N-(4-methylphenyl)-4H-1,2,4-triazol-3-amine

SMILES Cc1ccc(Nc2nnc(SCc3ccc(F)c(F)c3)[nH]2)cc1

InChI Key InChIKey=JCCLYBLQSDKYDK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17369   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17369(1,2,4-Triazole Compound, 27 | 5-{[(3,4-difluorophe...)
Affinity DataKi:  3.30nM ΔG°:  -11.4kcal/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed