BDBM175280 2-(4-(4-Nitrophenyl)thiazol-2-ylimino)thiazolidin-4-one (4a)

SMILES [O-][N+](=O)c1ccc(cc1)-c1csc(N=C2NC(=O)CS2)n1

InChI Key InChIKey=UGQVBGOXPMGUDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175280   

TargetProstaglandin G/H synthase 2 [E165G](Homo sapiens (Human))
Beni-Suef University

LigandPNGBDBM175280(2-(4-(4-Nitrophenyl)thiazol-2-ylimino)thiazolidin-...)
Affinity DataIC50:  4.60E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

LigandPNGBDBM175280(2-(4-(4-Nitrophenyl)thiazol-2-ylimino)thiazolidin-...)
Affinity DataIC50:  1.34E+4nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed