BDBM175352 Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (7)

SMILES CCOC(=O)C1=C(C)NC(=S)NC1c1ccccc1

InChI Key InChIKey=QMFBVGUFEGVPNG-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 175352   

TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Karachi

LigandPNGBDBM175352(Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydr...)
Affinity DataKi:  1.58E+4nM IC50:  3.56E+4nMAssay Description:Reaction mixture consisting of 25 µL of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 µL of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))TBA
LigandPNGBDBM175352(Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydr...)
Affinity DataIC50:  580nMAssay Description:Inhibition of Homo sapiens (human) dihydrofolate reductase using dihydrofolate as substrate incubated for 5 min prior to substrate addition by spectr...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM175352(Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydr...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of Cryptosporidium parvum recombinant DHFR using dihydrofolate as substrate incubated for 5 min prior to substrate addition by spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article