BDBM175376 1,3-Dimethyl-8-[4-{2-(homoveratrylamino)-2-oxoethoxy}-phenyl]xanthine (13i, RB-422)

SMILES COc1ccc(CCNC(=O)COc2ccc(cc2)C2=NC3C(N2)C(=O)N(C)C(=O)N3C)cc1OC

InChI Key InChIKey=NUPAVXPUUAMNMT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 175376   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Panjab University

LigandPNGBDBM175376(1,3-Dimethyl-8-[4-{2-(homoveratrylamino)-2-oxoetho...)
Affinity DataKi:  128nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Panjab University

LigandPNGBDBM175376(1,3-Dimethyl-8-[4-{2-(homoveratrylamino)-2-oxoetho...)
Affinity DataKi:  516nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Panjab University

LigandPNGBDBM175376(1,3-Dimethyl-8-[4-{2-(homoveratrylamino)-2-oxoetho...)
Affinity DataKi:  1.68E+3nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Panjab University

LigandPNGBDBM175376(1,3-Dimethyl-8-[4-{2-(homoveratrylamino)-2-oxoetho...)
Affinity DataKi:  6.00E+3nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed