BDBM17667 2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)methyl]-4-methoxy-1H-1,3-benzodiazole::CHEMBL292923::benzimidazole analogue, 44

SMILES COc1cccc2n(Cc3c(F)cccc3F)c(nc12)-c1c(F)cccc1F

InChI Key InChIKey=YEFVOKDOLXVJEU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17667   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM17667(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataEC50:  80nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM17667(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)
Affinity DataIC50:  7.30nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed