BDBM17694 2-aminobenzimidazole, 19::4-{[2-({4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phenyl}amino)-1-methyl-1H-1,3-benzodiazol-5-yl]oxy}-N-methylpyridine-2-carboxamide

SMILES CNC(=O)c1cc(Oc2ccc3n(C)c(Nc4ccc(Cl)c(CN5CCN(C)CC5)c4)nc3c2)ccn1

InChI Key InChIKey=WGONGMOZFNXPIC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17694   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM17694(2-aminobenzimidazole, 19 | 4-{[2-({4-chloro-3-[(4-...)
Affinity DataKi:  10nM ΔG°:  -10.8kcal/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed