BDBM17720 2,3-Diarylfuro[2,3-b]pyridine-4-amine, 16::2-(4-{2-[bis(propan-2-yl)amino]ethoxy}phenyl)-3-phenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-b]pyridin-4-amine

SMILES CC(C)N(CCOc1ccc(cc1)-c1oc2nccc(NCCN3CCNCC3)c2c1-c1ccccc1)C(C)C

InChI Key InChIKey=KNNAWFQMISAWMQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17720   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM17720(2,3-Diarylfuro[2,3-b]pyridine-4-amine, 16 | 2-(4-{...)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

LigandPNGBDBM17720(2,3-Diarylfuro[2,3-b]pyridine-4-amine, 16 | 2-(4-{...)
Affinity DataIC50:  44nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

LigandPNGBDBM17720(2,3-Diarylfuro[2,3-b]pyridine-4-amine, 16 | 2-(4-{...)
Affinity DataIC50:  180nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17720(2,3-Diarylfuro[2,3-b]pyridine-4-amine, 16 | 2-(4-{...)
Affinity DataIC50:  19nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed