BDBM17722 2,3-Diarylfuro[2,3-b]pyridine-4-amine, 18::3-phenyl-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-N-[2-(pyridin-4-yl)ethyl]furo[2,3-b]pyridin-4-amine

SMILES C(Cc1ccncc1)Nc1ccnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=RSRIBZZUPWIEDF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17722   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM17722(2,3-Diarylfuro[2,3-b]pyridine-4-amine, 18 | 3-phen...)
Affinity DataIC50:  4.70E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

LigandPNGBDBM17722(2,3-Diarylfuro[2,3-b]pyridine-4-amine, 18 | 3-phen...)
Affinity DataIC50:  80nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

LigandPNGBDBM17722(2,3-Diarylfuro[2,3-b]pyridine-4-amine, 18 | 3-phen...)
Affinity DataIC50:  180nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17722(2,3-Diarylfuro[2,3-b]pyridine-4-amine, 18 | 3-phen...)
Affinity DataIC50:  1.60E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed