BDBM177440 US9120749, 806::US9120749, 815

SMILES CNC1CCCN(C1)c1ccc(Nc2c(cnc3ccc(cc23)-c2cc(F)c(O)c(Cl)c2)C(C)=O)cn1

InChI Key InChIKey=NBKZPCDCUOTJOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177440   

TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Oncotherapy Science

US Patent
LigandPNGBDBM177440(US9120749, 806 | US9120749, 815)
Affinity DataIC50:  1.80nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Oncotherapy Science

US Patent
LigandPNGBDBM177440(US9120749, 806 | US9120749, 815)
Affinity DataIC50:  1.20nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In DepthDetails US Patent