BDBM177646 US9120769, 148::US9663470, 148

SMILES O=C(N1CCC[C@H]2[C@@H]1Cc1cc(ccc21)C#N)c1ccc2[nH]cnc2c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177646   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM177646(US9120769, 148 | US9663470, 148)
Affinity DataIC50:  214nMAssay Description:In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM177646(US9120769, 148 | US9663470, 148)
Affinity DataIC50:  214nMpH: 6.0Assay Description:n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...More data for this Ligand-Target Pair
In DepthDetails US Patent