BDBM177772 US10000475, Compound 1::US9120786, 1

SMILES FC(F)(F)Oc1ccc(Oc2ccc(cc2)-c2nc(N[C@H]3CCNC3=O)nc(n2)C#N)cc1

InChI Key InChIKey=XHEQEOBIFRPENG-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177772   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM177772(US10000475, Compound 1 | US9120786, 1)
Affinity DataIC50:  2.25E+3nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM177772(US10000475, Compound 1 | US9120786, 1)
Affinity DataIC50:  2.25E+3nMT: 2°CAssay Description:FLIPRTETRA Sodium Dye Assay with KCl: Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent