BDBM177854 US9120791, Example 76::US9603854, 76

SMILES CN1CCN(C[C@@H]2Cc3ccccc3CN2C(=O)c2cc3OCOc3cc2-c2cc(C(=O)N(c3ccc(O)cc3)c3ccc4n(C)ccc4c3)c3CCCn23)CC1

InChI Key InChIKey=FZJZTQONXQLEDJ-DHUJRADRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177854   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM177854(US9120791, Example 76 | US9603854, 76)
Affinity DataIC50:  17nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Mus musculus (Mouse))
Les Laboratoires Servier

US Patent
LigandPNGBDBM177854(US9120791, Example 76 | US9603854, 76)
Affinity DataIC50:  17nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
In DepthDetails US Patent