BDBM17805 N-(6-{[6-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)pyridin-3-yl]oxy}-1H-1,3-benzodiazol-2-yl)acetamide::benzimidazole-urea, 33

SMILES CC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)nc3)cc2[nH]1

InChI Key InChIKey=BDUFSIJFMWAXAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17805   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM17805(N-(6-{[6-({[2-fluoro-5-(trifluoromethyl)phenyl]car...)
Affinity DataIC50:  2.90nMpH: 7.4 T: 2°CAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed