BDBM178134 2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-1,4-diol (4)

SMILES Oc1ccc(O)c(c1)-c1nc2ncc(Cl)cc2[nH]1

InChI Key InChIKey=QIZJRQLCOYKHDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 178134   

TargetBeta-glucuronidase(Homo sapiens (Human))
Jamia Hamdard (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM178134(2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...)
Affinity DataIC50:  4.61E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
Universiti Teknologi Mara (Uitm), Puncak Alam Campus

LigandPNGBDBM178134(2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...)
Affinity DataIC50:  4.61E+4nMAssay Description:The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed