BDBM17830 (2S)-2-acetamido-N-[(2S,4S,5S)-4-hydroxy-5-{[(5S)-2-oxo-3-[3-(trifluoromethyl)phenyl]-1,3-oxazolidin-5-yl]formamido}-1,6-diphenylhexan-2-yl]-3-methylbutanamide::Hydroxyethylene Isostere-Based Compound, 13d
SMILES CC(C)[C@H](NC(C)=O)C(=O)N[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1cccc(c1)C(F)(F)F)Cc1ccccc1
InChI Key InChIKey=LLSDCSYISTWPMW-QDNWXXHKSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 17830
TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 2.62nM ΔG°: -11.9kcal/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair