BDBM17834 2-(2,6-dimethylphenoxy)-N-[(2S,4S,5S)-4-hydroxy-5-{[(5S)-2-oxo-3-phenyl-1,3-oxazolidin-5-yl]formamido}-1,6-diphenylhexan-2-yl]acetamide::Hydroxyethylene Isostere-Based Compound, 16a
SMILES Cc1cccc(C)c1OCC(=O)N[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1ccccc1)Cc1ccccc1
InChI Key InChIKey=ODZZSPNMADKGPQ-DYTOPAQESA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 17834
TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 8.05nM ΔG°: -11.2kcal/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair