BDBM179476 US9675697, Cpd. No. 34
SMILES COc1cc2c(cc1-c1c(C)n[nH]c1C)[nH]c1ccnc(-c3c(C)n[nH]c3C)c21
InChI Key InChIKey=QBBUJRPLGKCTAD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 179476
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 775nM ΔG°: -8.33kcal/mole IC50: 3.67E+3nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 1.20E+3nM ΔG°: -8.07kcal/mole IC50: 3.20E+3nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair