BDBM179868 US11147820, Compound Metopimazine acid::US9132134, Metopimazine-Acid (NG102)

SMILES CS(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCC(CC3)C(O)=O)c2c1

InChI Key InChIKey=PWQSSAWBTAKELO-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179868   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179868(US11147820, Compound Metopimazine acid | US9132134...)
Affinity DataKi:  14nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179868(US11147820, Compound Metopimazine acid | US9132134...)
Affinity DataKi: >100nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H1 receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179868(US11147820, Compound Metopimazine acid | US9132134...)
Affinity DataKi:  140nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179868(US11147820, Compound Metopimazine acid | US9132134...)
Affinity DataIC50:  310nMAssay Description:The functional antagonist assay was performed as described in Payne, S. L et al. (2002) J. Neurochem., 82: 1106-1117, hereby incorporated by referenc...More data for this Ligand-Target Pair
In DepthDetails US Patent