BDBM179945 US9133148, 2i

SMILES FC(F)(F)C(OC(=O)N1CCN(CC1)C(c1cocn1)c1cocn1)C(F)(F)F

InChI Key InChIKey=UJNMSEISYLPHCA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179945   

TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

US Patent
LigandPNGBDBM179945(US9133148, 2i)
Affinity DataIC50: >6.00E+3nMT: 2°CAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 uL, 1.0 mg/mL total protein concentration) were preincubated with varying concentration...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM179945(US9133148, 2i)
Affinity DataIC50:  210nMAssay Description:Inhibition of PLA2G7 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM179945(US9133148, 2i)
Affinity DataIC50:  270nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM179945(US9133148, 2i)
Affinity DataIC50:  600nMAssay Description:Inhibition of ABHD6 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed