BDBM179946 US9133148, 2j
SMILES Cc1cc(Cl)ccc1C(N1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)c1ccc(Cl)cc1C
InChI Key InChIKey=VXALLNCTVBYACN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 179946
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 uL, 1.0 mg/mL total protein concentration) were preincubated with varying concentration...More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Abide Therapeutics
Curated by ChEMBL
Abide Therapeutics
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLA2G7 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ABHD6 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair