BDBM179955 US9133148, 3f
SMILES CN(Cc1cccc(c1)-c1ccncc1)C(=O)OC(C(F)(F)F)C(F)(F)F
InChI Key InChIKey=RBZKWMMBPOHSDF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 179955
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 uL, 1.0 mg/mL total protein concentration) were preincubated with varying concentration...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of mouse MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 385nMAssay Description:Inhibition of rat MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant human full length MAGL expressed in HEK293 cells preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-b...More data for this Ligand-Target Pair