BDBM180074 US9133148, 10c
SMILES Cc1nn(cc1CN1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)-c1ccccc1
InChI Key InChIKey=QIMGORSOWHPBSK-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 180074
Affinity DataIC50: >6.25E+3nMT: 2°CAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 uL, 1.0 mg/mL total protein concentration) were preincubated with varying concentration...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of ABHD6 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Abide Therapeutics
Curated by ChEMBL
Abide Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PLA2G7 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair