BDBM18029 (6R)-6-({[1-(3-hydroxypropyl)-1,2,3,4-tetrahydroquinolin-7-yl]oxy}methyl)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phenyl)piperazin-2-one::CHEMBL372416::Ketopiperazine-based inhibitor, 9
SMILES COc1ccccc1COCCCOc1ccc(cc1)N1[C@@H](COc2ccc3CCCN(CCCO)c3c2)CNCC1=O
InChI Key InChIKey=HEFYJBZEIVFECQ-GDLZYMKVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 18029
Affinity DataIC50: 37nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair