BDBM182735 US10774056, Compound 001::US11542242, Compound 001::US9145412, Table 1, Compound 1
SMILES Nc1ccccc1NC(=O)c1ccc2nc(ccc2c1)N1CCNCC1
InChI Key InChIKey=BSYRUCVRUZESMD-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 182735
Affinity DataIC50: >2.00E+3nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Affinity DataIC50: 624nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Regenacy Pharmaceuticals
US Patent
Regenacy Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:For hERG inhibition assays, the cells used were HEK293 cells stably transfected with hERG (cell line obtained from Cytocentrics Inc. 3463 Magic Drive...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Regenacy Pharmaceuticals
US Patent
Regenacy Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:For hERG inhibition assays, the cells used were HEK293 cells stably transfected with hERG (cell line obtained from Cytocentrics Inc. 3463 Magic Drive...More data for this Ligand-Target Pair
Affinity DataIC50: 104nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair