BDBM182735 US10774056, Compound 001::US11542242, Compound 001::US9145412, Table 1, Compound 1

SMILES Nc1ccccc1NC(=O)c1ccc2nc(ccc2c1)N1CCNCC1

InChI Key InChIKey=BSYRUCVRUZESMD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 182735   

TargetHistone deacetylase 1(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM182735(US10774056, Compound 001 | US11542242, Compound 00...)
Affinity DataIC50: >2.00E+3nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM182735(US10774056, Compound 001 | US11542242, Compound 00...)
Affinity DataIC50:  624nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM182735(US10774056, Compound 001 | US11542242, Compound 00...)
Affinity DataIC50: >3.00E+4nMAssay Description:For hERG inhibition assays, the cells used were HEK293 cells stably transfected with hERG (cell line obtained from Cytocentrics Inc. 3463 Magic Drive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM182735(US10774056, Compound 001 | US11542242, Compound 00...)
Affinity DataIC50: >3.00E+4nMAssay Description:For hERG inhibition assays, the cells used were HEK293 cells stably transfected with hERG (cell line obtained from Cytocentrics Inc. 3463 Magic Drive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM182735(US10774056, Compound 001 | US11542242, Compound 00...)
Affinity DataIC50:  104nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent