BDBM184563 US9150581, RTI-7527-169
SMILES NC(=O)c1cccc(c1)-c1cc(cnc1F)C1CC2CCC1N2
InChI Key InChIKey=BVMMXDPNJVFASA-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 184563
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute
US Patent
Research Triangle Institute
US Patent
Affinity DataKi: 0.360nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute
US Patent
Research Triangle Institute
US Patent
Affinity DataKi: 870nMAssay Description:Compounds (10 mM) were also evaluated for inhibition of binding to a7 nAChR using [125I]iodoMLA as previously reported in Carroll et al. The binding ...More data for this Ligand-Target Pair