BDBM1851 3-[(2-tert-Butylphenyl)sulfanyl]-5,6-dihydro-4-hydroxy-6,6-diphenyl-2H-pyran-2-one::3-[(2-tert-butylphenyl)sulfanyl]-4-hydroxy-6,6-diphenyl-5,6-dihydro-2H-pyran-2-one::4-Hydroxy-5,6-dihydropyrone deriv. 42

SMILES CC(C)(C)c1ccccc1SC1C(=O)CC(OC1=O)(c1ccccc1)c1ccccc1

InChI Key InChIKey=KQGACGBFGJSRAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1851   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM1851(3-[(2-tert-Butylphenyl)sulfanyl]-5,6-dihydro-4-hyd...)
Affinity DataIC50:  49nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed