BDBM185612 US9156856, 23::US9493431, 23

SMILES Cc1cc(-c2oncc2S(=O)(=O)NC(=O)c2ccc(cc2)N2CCN(Cc3ccccc3-c3ccc(Cl)cc3)CC2)n(C)n1

InChI Key InChIKey=AXJQZFASFUNMSC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185612   

TargetApoptosis regulator Bcl-2/Glutathione S-transferase P(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM185612(US9156856, 23 | US9493431, 23)
Affinity DataKi:  447nM ΔG°:  -8.66kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM185612(US9156856, 23 | US9493431, 23)
Affinity DataKi:  447nM ΔG°:  -8.66kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent