BDBM185730 US9162979, 24-II

SMILES Cc1c(CC(=O)NCCO)cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1cccc(F)c1

InChI Key InChIKey=HYKQBYWDOROHEG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 185730   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Rottapharm Biotech

US Patent
LigandPNGBDBM185730(US9162979, 24-II)
Affinity DataIC50:  290nMT: 2°CAssay Description:The murine monocyte/macrophage cell line J774 is grown in Dulbecco's modified Eagle's medium (DMEM), enriched with glutamine (2 mM), HEPES (25 mM), p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin G/H synthase 1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM185730(US9162979, 24-II)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX-1 in mouse J774 cells using arachidonic acid as substrate assessed as inhibition of prostaglandin E2 production preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM185730(US9162979, 24-II)
Affinity DataIC50:  290nMAssay Description:Inhibition of LPS-induced COX-2 in mouse J774 cells using arachidonic acid as substrate assessed as inhibition of prostaglandin E2 production preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed