BDBM1861 (6R)-4-hydroxy-3-{[5-methyl-2-(propan-2-yl)phenyl]sulfanyl}-6-phenyl-6-(2-phenylethyl)-5,6-dihydro-2H-pyran-2-one::4-Hydroxy-5,6-dihydropyrone deriv. 52
SMILES CC(C)c1ccc(C)cc1SC1C(=O)C[C@@](CCc2ccccc2)(OC1=O)c1ccccc1
InChI Key InChIKey=LHYLEOOHWAOPAV-ZBAATNBSSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 1861
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataIC50: 130nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair