BDBM18621 1-(2-{[(18Z)-13-hydroxy-12-methoxy-3,5,5-trimethyl-17-oxa-6-azatetracyclo[8.8.0.0^{2,7}.0^{11,16}]octadeca-1(10),2(7),3,8,11,13,15-heptaen-18-ylidene]methyl}thiophen-3-yl)ethan-1-one::Ketone, 18

SMILES COc1c(O)ccc2OC(=Cc3sccc3C(C)=O)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key InChIKey=VMJXNOKTPKNUJR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18621   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18621(1-(2-{[(18Z)-13-hydroxy-12-methoxy-3,5,5-trimethyl...)
Affinity DataIC50:  0.300nM EC50:  0.600nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed