BDBM187195 US9670181, 71 4-((2-butyl-6-methoxyquinolin-3-yl)methyl)-6,7-dimethoxy-1-propylisoquinolin-3-ol

SMILES CCCCc1nc2ccc(OC)cc2cc1Cc1c(O)nc(CCC)c2cc(OC)c(OC)cc12

InChI Key InChIKey=CGBQVRCDUIRQBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187195   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM187195(US9670181, 71 4-((2-butyl-6-methoxyquinolin-3-yl)m...)
Affinity DataIC50:  93nMpH: 7.4 T: 2°CAssay Description:The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE® from Perkin Elmer). This c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent