BDBM188513 3,7,7-trimethyl-4-phenyl-2H,5H,6H,7H,8H-pyrazolo[3,4-b]quinolin-5-one (15)

SMILES Cc1[nH]nc2nc3CC(C)(C)CC(=O)c3c(-c3ccccc3)c12

InChI Key InChIKey=IRFRJPKEKZWJEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 188513   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM188513(3,7,7-trimethyl-4-phenyl-2H,5H,6H,7H,8H-pyrazolo[3...)
Affinity DataIC50: >3.33E+4nMpH: 7.5 T: 2°CAssay Description:Purified GSK3beta was incubated with tested compounds in doses in the presence of 4.3 uM of ATP and 1.5uM peptide substrate (Peptide 15, Caliper, MA)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM188513(3,7,7-trimethyl-4-phenyl-2H,5H,6H,7H,8H-pyrazolo[3...)
Affinity DataIC50: >3.33E+4nMpH: 7.5 T: 2°CAssay Description:Purified GSK3beta was incubated with tested compounds in doses in the presence of 4.3 uM of ATP and 1.5uM peptide substrate (Peptide 15, Caliper, MA)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed