BDBM188811 US9169260, 77

SMILES Fc1cc(cc(F)c1-n1nc(cc1NC(=O)c1cnn2cccnc12)C1CCNCC1)C1CC1

InChI Key InChIKey=KRLFCFMEUJMYAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188811   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM188811(US9169260, 77)
Affinity DataIC50: <100nMpH: 7.2Assay Description:The kinase activity of IRAK-4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phos...More data for this Ligand-Target Pair
In DepthDetails US Patent