BDBM18941 2-(3,5-dibromo-4-{4-hydroxy-3-[4-(trifluoromethyl)phenoxy]phenoxy}phenyl)acetic acid::4-hydroxy thyromimetic, 13d

SMILES OC(=O)Cc1cc(Br)c(Oc2ccc(O)c(Oc3ccc(cc3)C(F)(F)F)c2)c(Br)c1

InChI Key InChIKey=ZOOUPJHRNKSBCT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18941   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM18941(2-(3,5-dibromo-4-{4-hydroxy-3-[4-(trifluoromethyl)...)
Affinity DataIC50:  326nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of Insubria

Curated by ChEMBL
LigandPNGBDBM18941(2-(3,5-dibromo-4-{4-hydroxy-3-[4-(trifluoromethyl)...)
Affinity DataIC50:  9.55nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of Insubria

Curated by ChEMBL
LigandPNGBDBM18941(2-(3,5-dibromo-4-{4-hydroxy-3-[4-(trifluoromethyl)...)
Affinity DataIC50:  9.5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed