BDBM18974 3-methyl-1-phenyl-N-[4-(2-sulfamoylphenyl)phenyl]-1H-pyrazole-5-carboxamide::CHEMBL139121::pyrazole-based inhibitor, 22d
SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1ccccc1
InChI Key InChIKey=FSHMKQSLAPAUNB-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 18974
Affinity DataKi: 198nM ΔG°: -9.05kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were determined ...More data for this Ligand-Target Pair
Affinity DataKi: 198nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+3nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
Affinity DataKi: >2.10E+4nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair