BDBM189807 US9174993, 45::US9221828, 45

SMILES Nc1n[nH]c2nc(cnc12)-c1ccc(NS(=O)(=O)c2cc(ccc2F)C#N)cc1

InChI Key InChIKey=AUFBRUCYTNGAAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189807   

TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM189807(US9174993, 45 | US9221828, 45)
Affinity DataIC50:  47nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM189807(US9174993, 45 | US9221828, 45)
Affinity DataIC50:  47nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent