BDBM190916 US9670203, Compound 1.80
SMILES O=C(N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12)N[C@@H]1CCCc2ccccc12
InChI Key InChIKey=VZPYATCCROEPNC-CHQQOIJLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 190916
TargetRAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D](Homo sapiens (Human))
Beigene
US Patent
Beigene
US Patent
Affinity DataIC50: 500nMT: 2°CAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMT: 2°CAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair