BDBM19131 CHEMBL419758::JMC505425 Compound 7::N-(4-phenyl-1,3-thiazol-2-yl)-7-sulfanylheptanamide::NCH-31

SMILES SCCCCCCC(=O)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=LUXAHBUKMVESIS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 19131   

TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  41nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  48nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  32nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human HDAC1 by HDAC-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Nagoya University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human HDAC9 by HDAC-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human HDAC6 by HDAC-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed