BDBM191764 US9187406, Compound 1

SMILES COC(=O)C(C(=O)\C=C\c1ccc(O)c(OC)c1)C(=O)\C=C\c1ccc(O)c(OC)c1

InChI Key InChIKey=GYWBYEKCMUYXGS-JMQWPVDRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 191764   

TargetNeutrophil collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191764(US9187406, Compound 1)
Affinity DataIC50:  3.50E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCollagenase 3(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191764(US9187406, Compound 1)
Affinity DataIC50:  1.50E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191764(US9187406, Compound 1)
Affinity DataIC50:  4.80E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191764(US9187406, Compound 1)
Affinity DataIC50:  1.60E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent