BDBM191768 US9187406, Compound 4

SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(CN(C)C)cc2)ccc1O

InChI Key InChIKey=NCQNHYSEAFOYHX-HZOWPXDZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191768   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191768(US9187406, Compound 4)
Affinity DataIC50:  1.70E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCollagenase 3(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191768(US9187406, Compound 4)
Affinity DataIC50:  2.50E+5nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191768(US9187406, Compound 4)
Affinity DataIC50: >2.50E+5nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent