BDBM191769 US11608309, Compound 6::US9187406, Compound 6
SMILES COc1cc(\C=C\C(=O)C(C(=O)Nc2ccccc2)C(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
InChI Key InChIKey=XOWCANZIJBUHCZ-WFYKWJGLSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 191769
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York
US Patent
The Research Foundation of State University of New York
US Patent
Affinity DataIC50: 8.50E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York
US Patent
The Research Foundation of State University of New York
US Patent
Affinity DataIC50: 8.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair