BDBM192503 US9187474, 18
SMILES CNc1cc2nc(C)c(cc2cn1)-c1cc(NC(=O)NCCC(C)(C)C)ccc1F
InChI Key InChIKey=ACGNJFZSGIKELN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 192503
Affinity DataIC50: 35nMAssay Description:Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Deciphera Pharmaceuticals
US Patent
Deciphera Pharmaceuticals
US Patent
Affinity DataIC50: 20nMAssay Description:Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Deciphera Pharmaceuticals
US Patent
Deciphera Pharmaceuticals
US Patent
Affinity DataIC50: 37nMAssay Description:Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...More data for this Ligand-Target Pair