BDBM19268 Acridone-Based Inhibitor, 3::ethyl 9-oxo-9,10-dihydroacridine-3-carboxylate

SMILES CCOC(=O)c1ccc2c(c1)[nH]c1ccccc1c2=O

InChI Key InChIKey=MSRVWFZBNPFFSH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19268   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM19268(Acridone-Based Inhibitor, 3 | ethyl 9-oxo-9,10-dih...)
Affinity DataIC50:  59nM EC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed