BDBM192709 AGF117

SMILES Cc1sc(cc1CCCCc1cc2c(nc(N)[nH]c2=O)[nH]1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=HNWBLBBIBWGFBP-AWEZNQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192709   

TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM192709(AGF117)
Affinity DataIC50:  7nMpH: 7.5Assay Description:GARFTase activity was determined by measuring the rate of 5,8-dideazatetrahydrofolate production in the presence of varying concentrations of antifol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed